Help for Lollipop, a blind mare

From Lisa, owner of the mare, Lollipop:

“We’ve spoken about my blind mare Lollipop and how the transition to her new home (with her companion) was a real challenge. I really wasn’t sure what to do and at that point I called you.

I want to give you an update about her. The CBD saved her life! After watching her suffer for 5 very long weeks and walk miles of circles in her paddock, she has finally stopped.

Thursday was her best day ever – no circle walking after 6 a.m. For the first 6 days of treatment, there was some intermittent, but brief circling. I have a security camera on her, so I have been able to closely monitor her progress. It is like the switch that got flipped on during our move, has finally been turned off. I cannot express the relief this has given me. All day Thursday after breakfast, no walking, same yesterday, and again this morning, no walking. Also, during those first 5 weeks, she was walking so much that she was laying down a lot. She was physically exhausted – poor girl. She is laying down less frequently now and already appears to be filling out a bit. She had dropped quite a bit of weight.

For the record:

I started her on 28g twice daily (560mg CBD/day) combined with 500mg B1 crumbles twice daily (1000mg/day). I saw absolutely no adverse side effects. She was alert, engaging, eating and drinking normally. I didn’t really intend on starting with this high of a dose, but since this where I accidentally started, I decided to just stick with it – glad I did.

Friday I began dropping her CBD intake. She received 520mg CBD for the day. I think I will drop her dosage every 3rd day as long as her mental state remains stable.

I must admit that the CBD therapy was a “hail Mary” throw in my book. I had exhausted all my other options. This was going to be my last attempt to avoid euthanasia and I came in skeptical -Having never used CBD for medicinal purposes. Well, I am a confirmed believer! This stuff works!

My goal is to get her down to 200mg/day as I think I will continue to use this product for maintenance. She is 26 and I know our time together is limited. All I ever wanted was to give her a few more comfortable years of retirement in our new home together. It seems we are on the right path to achieve that dream.

Thank you for everything!”

Is it safe to use CBD for a dog with anxiety?

Having an anxious dog can be difficult – not only on your dog, but on your heart (and possibly your property!)

With the recent rise in popularity of CBD oil products, many dog parents wonder if CBD could be a good option to help their dog with anxiety.

Causes & Signs of Anxiety in Dogs

While 20-40% of dogs experience separation anxiety, nearly all dogs experience some kind of general anxiety or fear at one time or another.

According to the American Kennel Club, there are three main causes of anxiety in canines. They are fear (of situations, noises, people, or other dogs), separation, or old age. Some senior dogs begin to show signs of anxiety, especially if they develop cognitive dysfunction syndrome (CDS).

Signs of anxiety could include:

  • Urinating or defecating in home (even after being let outside)
  • Excessive whining and barking
  • Running and hiding
  • Aggression
  • Destruction
  • Pacing or restlessness
  • Panting
  • Drooling

Why CBD for Anxiety?

CBD is one of over 100 identified cannabinoids, compounds that are found in cannabis. All high-level animals (mammals, birds, reptiles and fish), have an endocannabinoid system in their body. The endocannabinoid system is the system in the body that interacts with CBD to give you the positive effects that CBD has to offer.

One of the most popular uses of CBD is to treat anxiety. In fact, while there is a growing body of research around the many medical benefits of CBD, one of the most studied effects of CBD is as an anxiolytic (anti-anxiety).

However, most of the research about CBD is in reference to humans. We apply much of what we believe about CBD to dogs, because we know that all animals have an endocannabinoid system, and that system works the same regardless of species.

Studies on CBD Oil for Dogs

Studies of CBD on dogs are few and far between right now, but here are some of the more notable ones.

Pharmacokinetics, Safety, and Clinical Efficacy of Cannabidiol Treatment in Osteoarthritic Dogs

This study focused on the effectiveness of CBD as a pain reliever in arthritic dogs. The result was decreased pain in the dogs (observed by increased activity) without noticeable side effects.

The effect of oral cannabidiol administration on seizure frequency in dogs with intractable idiopathic epilepsy

In this study, dogs maintained their current epilepsy medications, while also receive CBD. The average reduction in epileptic symptoms was 33%.

These two studies on using CBD for pain and epileptic seizures, are consistent with study results from trials on humans. We deduce from what we know about the endocannabinoid system that CBD also helps sooth anxiety in dogs, just as it does in humans.

Customers Using CBD on Dogs with Anxiety

Here are a few testimonials from real customers that have used our CBD oil for their dogs to treat anxiety and PTSD.

“Doris is a stray that came into the Riverside, CA shelter and was due to be euthanized so we snatched her up. Doris has had lots to overcome, including health issues and what we would call PTSD. She’s doing better than we ever thought, with lots of love, good food, a warm bed and CBD twice a day to help with anxiety, she’s doing great.”

“Coco is a 12 year old miniature pinscher. She gets CBD to help with her anxiety and helps her to stop chewing on her front legs and paws.”

THC Warnings for Dogs

There is one very important warning that every dog owner must not ignore. THC is toxic to dogs and should not be present (not even in a tiny amount) in any CBD product given to dogs.

Many CBD brands are inconsistent with labeling. It is wise to check with your manufacturer to ensure that there is 0% THC in your product. The legally allowable limit of THC in CBD products (under the 2018 Fam Bill), is 0.3%, but this is dangerous to canines.

0% THC products can and do exist for dogs, you just need to find them. Request 3rd party verification from companies you purchase CBD from.

Types of CBD for Dogs

CBD can be administered to dogs through treats, tinctures, sprays or topical salves.

CBD Treats for DogsWe offer CBD dog treats that contain 2mg of CBD in each treat. Our dosing chart can help you find the appropriate amount of CBD for your dog.

We also have a tincture that can be administered in the side of the mouth. Many dogs will lick it right out of the syringe. You can also put it on a small amount of bribe food if necessary and give that on an empty stomach, but in the side of the mouth is best. There is no added flavor, and our product contains 0 THC.

Best CBD Dose for Dogs

In the first study about using CBD for dogs, the trial used 2 mg of CBD per kilogram of body weight. This is just a starting point. Dosing of CBD in dogs with anxiety really depends on each individual dog.

Finding your dog’s optimal dose of CBD will take some trial and error. It’s important to always start with the smallest dose possible, and add gradually while monitoring symptoms.

Here are our recommended “perfect dosing steps:”

  1. Start with 2mg of CBD per kg of body weight, and maintain that dose for two days. Provide the CBD at least a half an hour before your dog’s morning meal so that it is more readily absorbed.
  2. Notice any side effects or reactions (extremely rare.) If your dog has any adverse effects, halve the dose for the next time and provide the new, smaller dose for a few days before trying to build back up.
  3. It can take some time for CBD to build up in your dog’s system. In order to get a good idea of how it is working, it’s important to increase the dose slowly.
  4. Continue to increase the amount of CBD per dose, until you see a decrease in benefit, or have any adverse reactions.

If you have questions about using CBD, you can send us a message.

We also advise you to seek out the advice of a veterinarian, especially if your dog is taking other medications. Depending on your state’s laws, some veterinarians may not be able to discuss CBD with you, but a search for “Holistic Vet” will give you a good start!


These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

All content found on the Hope Botanicals website were created for informational purposes only. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.

Does CBD work as a sleep aid?

Does CBD Work as a Sleep Aid?

More than 70 million Americans are affected by sleep disorders. There are more than 80 identified sleep disorders that include conditions such as insomnia, sleep apnea, restless leg syndrome and circadian rhythm disorders.(1) In fact, the Centers for Disease Control (CDC) has said that insufficient sleep is a public health epidemic.

Getting too few hours of sleep, or poor quality sleep, is linked to a myriad of health issues like heart disease, diabetes, obesity, depression, and inflammation.(2) Conversely, adequate sleep is great for your immune system, allows your body to repair itself, processes emotions and experiences from your day, and helps maintain metabolic function. (3)

It’s no wonder that most of us are obsessed with getting a good night’s sleep! In addition to proper nutrition and exercise, adequate sleep is essential to good health.

CBD Oil and the Endocannabinoid System

With the exploding interest in cannabidiol (CBD) as a potential natural remedy for almost everything, it makes sense that many people have started to turn to CBD, to help them sleep.

CBD is a phytocannabinoid, or, a chemical compound that naturally occurs in cannabis. There are currently over 100 phytocannabinoids in cannabis that have been identified. Cannabinoids interact with the body’s endocannabinoid system (ECS) to balance pleasure, energy and well-being. A healthy, operating ECS works to gently prod the body back to a healthy state when facing injury or disease.

You can learn more about this by reading our article about the Endocannabinoid System and how CBD works with it.

Studies on CBD as a Sleep Aid

The question is, even though many people are trying CBD products to help them sleep… is it working?

Thorough studies on CBD as a sleep aid are still few and far between, but here are some of the more notable ones:

Cannabidiol in Anxiety and Sleep: A Large Case Series

In this study, CBD was given to 72 adults that were being clinically treated for anxiety and poor sleep. The patients were given 25mg of CBD after dinner. A few patients ended up increasing their CBD dose throughout the trial. After one month, 66.8% of patients reported better sleep, and 79.2% reported a decrease in anxiety symptoms.

Effectiveness of Raw, Natural Medical Cannabis Flower for Treating Insomnia under Naturalistic Conditions

This study looked at the symptoms and cannabis administration of 409 patients with perceived insomnia. This study is not explicitly about CBD, and some patients used cannabis products containing THC. However, the summary states that, “Cannabidiol (CBD) was associated with greater statistically significant symptom relief.” This is a somewhat broad strokes study but does show potential promise.

Effect of cannabidiol on sleep disruption induced by the repeated combination tests consisting of open field and elevated plus-maze in rats

PTSD patients often report insomnia and REM sleep abnormalities. In this study, researchers compared the effects of CBD on sleep in normal rats vs. rats they induced PTSD symptoms in. They confirmed that CBD does have anxiety reducing effects. When given CBD to aid in non-REM and REM sleep, the study showed that CBD helped to improve REM sleep, but not non-REM sleep.

Cannabis, Cannabinoids, and Sleep: a Review of the Literature

A review of the available research was summarized to suggest that annabidiol (CBD) may have therapeutic potential for the treatment of insomnia.

In this article by Consumer Reports, Dr. Joseph Maroon, MD suggests that CBD may work more indirectly with sleep by eliminating other factors that may keep you awake. Reducing pain, anxious thoughts or other negative symptoms with CBD oil, may in turn help you to sleep better.

To summarize, CBD may treat many of the root causes of poor sleep, allowing you to sleep better, but may not directly cause you to sleep better.

Customer Testimonials

Even though there isn’t an overwhelming body of evidence to suggest that CBD is a cure-all sleep aid, we do have anecdotal evidence from several customers. Here is what some of our customers have to say:

Customer Sarah F. says, “My hormones have been all over the place since I had ovarian cancer two years ago. The worst part is that it affects my sleep. I tried the tincture, and now I can get to sleep without a problem! Sometimes I wake up at 1 or 2 in the morning, but I just take a little more and fall back to sleep pretty quickly. Thank you!”

Guidelines for Taking CBD for Insomnia & Sleep Issues

Hope Botanicals offers CBD Oil products in tinctures, gel caps and gummies. Most of the studies that we looked at used 25mg-50mg as the dose, and were administered after dinner, or about one hour before bed.

For a more in-depth explanation about how much CBD to take, please read our article.

It is important to note that most people on a CBD regimen report that the positive effects of CBD build up over time, and are not always immediate.

The effectiveness of CBD depends largely on the underlying causes of a sleep disorder, individual factors such as how quickly CBD is metabolized, and the dose.

There are virtually no reported ill effects of CBD, as opposed to many pharmaceuticals that are available to use as sleep aids. Overall, CBD is a very safe and natural supplement that can benefit many people.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
All content found on the Hope Botanicals website were created for informational purposes only. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.

(1) https://www.sleephealth.org/sleep-health/the-state-of-sleephealth-in-america/
(2) https://www.healthline.com/nutrition/10-reasons-why-good-sleep-is-important
(3) https://www.healthline.com/nutrition/how-much-sleep-you-need#section1

Is CBD an effective sleep aid?

how much cbd should I take? Picture of a dropper of CBD oil

How Much CBD Should I Take?

Probably the most common question we get asked is, “how much CBD should I take?” or “how much CBD should I give my dog/horse/animal?” However, figuring out an ideal CBD dosage isn’t completely straightforward.

There are several factors to consider when starting a CBD regimen. Things like what condition you are treating, the delivery method (tinctures, soft gels, pellets, etc.), concentration of CBD in the product you are using, and your personal sensitivity/responsiveness to CBD.

We will look at each of these factors in turn.

Purity of CBD Product

Before you can decide how much CBD you will take, you must know the concentration of CBD in your product.

The concentration of CBD varies from product to product. Unfortunately, many producers will leave this information off the label, and you won’t know how much CBD your product actually contains. Because this isn’t regulated, it is up to you to do your research and request this information from the manufacturer. Reputable manufacturers will conduct 3rd party testing to confirm the concentration of their products.

We include this information for all our products, which makes measuring and dosing easy and accurate!

Form of CBD Product

You can get CBD in many different forms including tinctures, gel caps, gummies, topical salves and balms, and inhalants.

Each of these will have different concentrations of CBD in them. They also have different levels of bioavailability, and reaction and duration times.

Usually an oral supplement like a tincture or gel cap will last longer in your system than something administered topically. Oral supplements will work in your system roughly 4-8 hours, and topical supplements will last roughly 2-4 hours. It is important to know that this varies for everyone, based on how quickly you metabolize CBD, etc.

Most people find that they can feel topical CBD products working within about 15 minutes of application, and oral supplements within about 30 minutes of taking.

What Illness or Condition are you Treating?

Another factor to consider when figuring out how much CBD to take is what condition you are treating.

Micro Doses (up to 20mg per dose, two times a day)

Low (or “micro”) doses are usually appropriate for conditions like headaches, sleep disorders, nausea and general stress.

Standard Doses (10-100mg per dose, two times a day)

Mid-range doses are recommended for treating conditions like pain, autoimmune disorders, fibromyalgia, depression and anxiety, IBS and autism.

High Doses (50-800mg per dose, two times a day)

Therapeutic (high) doses are recommended for cancer, seizure disorders, liver disease and other life threatening illnesses.

Someone trying CBD for general wellness and to treat minor aches and pains would start off with a much smaller dose than someone battling aggressive cancer.

Individual Factors

Given the ranges above, how each person reacts to CBD is highly individual. Everyone processes and metabolizes CBD differently. Depending on the state of your endocannabinoid system, you can be more or less sensitive to CBD.

These things are nearly impossible to tell up front, until you have started a CBD regimen and have begun to experiment with it.

Other things that can influence how you react to CBD are your body weight, other medications that you are taking, and your diet and overall health.

If you have any questions about medications that you are currently taking, you should reach out to your medical doctor.

Finding Your Optimal CBD Dose

Ultimately, determining your perfect dose amount is done through trial and error. Always start with the minimum dose you think you need, and add from there.

  1. Start with a minimum dose and maintain that dose for two days. Take your CBD at least a half an hour before eating so that it is more readily absorbed.
  2. Notice any side effects or reactions (extremely rare.) If you have any adverse effects, halve your dose and take this new, smaller dose for a few days before trying to build back up.
  3. Note that it does take time for CBD to build up in your system. This is why it is important to increase your doses slowly, to allow you to get a good idea of how you feel.
  4. Continue to increase your CBD dose, until you experience a decrease in benefit, or have any adverse reactions.

The great news is that it is nearly impossible to “overdose” on CBD, and there are no known fatalities from overdosing on cannabis. Note that this article is specific to CBD, without the presence of THC.

What other questions do you have about how much CBD to take?

Disclaimer : All content found on the Hope Botanicals website has been created for informational purposes only. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.

how much CBD should I take?

How to Use CBD for your dog

How to Use CBD for Your Dog

There are a myriad of conditions that can afflict dogs which can by helped by the use of CBD.  Although veterinarians can’t prescribe CBD, some are willing to talk about the possible benefits of CBD for your dog, and even give you advice about using it.

How CBD Works in Dogs

All animals have an endocannabinoid system. The endocannabinoid system in dogs is part of what maintains the natural balance in the body and it is stimulated by endocannabinoids, which are produced in the body. However, the endocannabinoid system can also be stimulated by external cannabinoids, such as Cannabidiol (CBD.)

The endocannabinoid system is made up of two types of receptors. Your dog has:

  • CB1 receptors– located in the brain, nervous system, glands and organs
  • CB2 receptors– located in the regulatory cells of the immune system

Humans have these same receptors as well, but dogs actually have the highest concentration of CB1 and CB2 receptors of any animal!

CBD works by targeting the endocannabionid receptors, restoring balance when things are out of whack. That’s why CBD so good for so many different ailments.

You can read more about the endocannabinoid system and how it works in our article, How the Endocannabinoid System Works with CBD.

Is CBD safe for your dog?

The first question every dog parent asks is, “is this safe for my dog?” Cannabis has actually been used in veterinary medicine for thousands of years! There is evidence of the ancient Greeks using it to treat colic and horses, and even to treat battle wounds.

However, when speaking specifically about dogs, its vital to make a distinction between CBD and THC. (You can read more about CBD vs. THC in this article.) CBD is 100% safe for animals, but there are some important things to be aware of to make sure you are getting a pet-safe product.

While CBD is safe for your dog, THC is not. A CBD product for dogs should never contain any amount of THC. Even the smallest amount of THC can spell big trouble for your pup.

Dogs are highly sensitive to THC because, as previously mentioned, they have much higher concentrations of receptors in their endocannabinoid system. Even the tiniest amount of THC will quickly overload them and lead to toxicity.

Any CBD product you purchase should clearly state 0 THC on the label.  If it is not clear on the label, don’t buy it.

What conditions can CBD help with in dogs?

Because of all the many wonderful benefits of CBD, it’s difficult to think of a condition or ailment that wouldn’t somehow benefit from a CBD regimen! Some of the most common conditions that our customers approach us for are discussed here.

CBD and glaucoma in dogs

One of the neatest things we have seen CBD do for older dogs is help with glaucoma.  The compounds in cannabis reduce intraocular pressure in patients with glaucoma.  With my own older dog, her eyes cleared up within 10 days of starting CBD and have stayed clear on a daily dose. This is not an unusual benefit of giving CBD to your dog!

CBD and Fatty Tumors in dogs

These type of tumors are benign but can become quite big and bothersome.  A customer reached out and said her dog had a fatty tumor the size of a grapefruit.  We worked to find her optimal dose, and she committed to giving CBD twice a day.  Within 10 days the tumor shrunk to the size of an orange.  We’ve had multiple customers use CBD for fatty tumors with great success.

CBD and dogs with arthritis

Arthritis is a huge issue for dogs. Arthritis is the inflammation of joints that cause aching, pain and other degenerative illnesses.  As CBD is a pain reliever, it targets aching joints and gives your dog relief.   It also soothes the chronic inflammation that prevents your pet from healing properly.  A consistent treatment plan using CBD for arthritis can have huge benefits for dogs.

This is a great study on CBD for arthritis:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC16904/

“I have an 11 year old lab that was developing arthritis in her hips. Vet said she will probably always be on meds from now on. My thought was to give this a 30 trial period if it works great if not back to the prescription meds. After 1 week on the medium dose for a 100 lb. dog she has already shown improvements! Can’t wait to see what the next couple of weeks will bring.” – Katie M. (https://hopebotanicals.com/2018/06/arthritis-relief-for-maggie/)

CBD and dogs with allergies

Allergies can be caused by many things including diet and environmental factors. Determining the cause of the allergies is always the first step.  Adding CBD to your dog’s diet will help boost the immune system and help with the inflammatory response in the body.  CBD will definitely help with the itching and scratching that can plague your dog.

Seizures in dogs and CBD

Seizures in dogs are a debilitating issue and can cause owners much distress.  Conventional pharmaceutical drugs have negative side effects. Many owners are seeking other, more natural options.   Even with medication, up to 30 percent of dogs with epilepsy continue to experience seizures. CBD has been shown to help reduce seizures substantially.

This article from the National Institutes of Health is very informative and a must read for people dealing with seizures in their dogs. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767492/

If your dog’s ailment isn’t discussed above, additional research links can be found here: https://www.ncbi.nlm.nih.gov/pubmed/

Administering CBD to your dog

We offer a couple of convenient ways to administer CBD to your dog. Because dogs are much smaller than humans, and therefore more sensitive to CBD, care must be taken when dosing. We always advise to start with the smallest recommended dose, and wait a couple of days to increase the dose to achieve your desired result.

First, we sell a tincture that can be administered in the side of the mouth. There is no added flavor, and most dogs will accept it without issue. If that can’t be accomplished, then sprinkling the dose on a small amount of bribe food between meals is an option. Learn more about our CBD Tincture for Dogs here: https://hopebotanicals.com/product/cbd-tincture-for-pets-natural-flavor/






CBD Treats for DogsWe also offer beef-flavored CBD treats. These can be given any time you would normally offer your dog a treat. Each treat has 2mg of CBD. You can use the dosing chart above to figure out how much CBD is appropriate for your dog each day, and then feed treats accordingly. Learn more about our CBD Treats for Dogs here: https://hopebotanicals.com/product/750-mg-pcr-soft-chews-for-dogs/






Finally we offer a salve and a liniment gel that can be used topically on sore joints or muscles. We sell them as people and horse products, but they are safe for use on dogs as well.

CBD will likely be beneficial and a great addition to your dog’s daily regime.  I, and my customers, have found it to be very effective for a number of conditions as well.  I hope you choose to try this natural alternative for your dog’s health.

how the endocannabinoid system works with CBD

How the Endocannabinoid System Works with CBD

In order to fully understand how CBD is beneficial to us, it’s important to understand the endocannabinoid system.

The Endocannabinoid System

The endocannabinoid system is the body system that CBD interacts with to give you all of the positive benefits of a CBD regimen. All mammals, birds, reptiles and fish have an endocannabinoid system.

Our bodies have many systems. Our circulatory system exists to circulate blood and transport important nutrients throughout the body. Our respiratory system takes in oxygen from our surroundings and rids the body of carbon dioxide. Our digestive system breaks down food and converts it to energy in the body.

If we could sum up the function of the endocannabinoid system in one word, it would be: BALANCE.

The endocannabinoid system (ECS) exists to keep our bodies in a sort of “sweet spot.” The ECS balances pleasure, energy and well-being. It also gently prods the body back to a healthy state when facing injury or disease.

The importance of the endocannabinoid system can’t be overstated! It plays a critical role in the regulation of disease in our body. It heavily supports the immune system by keeping the immune system from being either over- or under-active.

The endocannabinoid system regulates all kinds of things, like inflammation, pain, bone health, growth of new nerve cells, fat and sugar processing, mood, energy, brain health, and hormone balance. We are hard-pressed to think of a disease or condition that isn’t related to one of those things!

The body has many internal processes that are continually either building things up or breaking them down. The ECS is constantly monitoring these processes to make sure that there is the right balance of building and breaking. When there is too much of one or the other, the ECS swoops in to restore the balance.

Think of it as the “behind the scenes” system that is working to make sure that your other body systems are all operating optimally.

Endocannabinoids and Phytocannabinoids

Cannabinoids are chemical compounds naturally found in cannabis. Endo means “within or inner,” and Phyto means “plant.” All this means is that endocannabinoids are cannabinoids that our body produces, and phytocannabinoids are cannabinoids that come from a plant, cannabis.

In 1992, Dr. Raphael Mechoulam discovered that animal bodies produce endocannabinoids.  Endocannabinoids are a type of neurotransmitter. Neurotransmitters are chemical messengers in the body that transfer signals between neurons in the nervous system.

The use of “cannabinoid” is a little confusing, but he termed these neurotransmitters “endocannabinoids” because they were so similar to the plant-based cannabinoids found in cannabis.

The ECS makes heavy use of endocannabinoids to do its job of keeping the body in a balanced state. Bradley E. Alger, Ph. D. calls endocannabinoids a “bridge between body and mind.”

CBD the Super Phytocannabinoid

There are currently over 100 phytocannabinoids that have been identified in cannabis. However, there is not extensive research on almost 90% of them!

Two of the most studied phytocannabinoids are cannabidiol (CBD) and tetrahydrocannabinol (THC.) CBD is the most plentiful phytocannabinoid found in all varieties of the cannabis plant. (You can read more about cannabis varieties and the difference between hemp, hemp oils and hemp seed oil in this blog post: https://hopebotanicals.com/2019/03/cbd-oil-vs-hemp-oil/)

THC also gets a lot of attention because it is the compound in cannabis responsible for the “high” that cannabis users experience.

The “Bliss Molecule”

It’s difficult to understand the full scope of what the endocannabinoid system does for the body, and how cannabinoids like CBD can help, without talking about anandamide!

Anandamide is a type of endocannabinoid neurotransmitter that has been nicknamed the “bliss molecule” because it is a pleasure and reward regulator.

Remember that endocannabinoids are made inside the human body? If anandamide had a phytocannabinoid (remember, plant-based cannabinoid) twin, it would be tetrahydrocannabinol (commonly known as THC.)

(If you want to impress your friends at your next barbeque, you can tell them that anandamide is an endogenous analogue of THC. That’s the scientific term for all of this!)

THC is the compound in cannabis responsible for the “high,” because it acts like a major flood of this bliss chemical.

The Endocannabinoid System Receptors

The Endocannabinoid System is made up of two types of receptors: CB1 and CB2. CB1 receptors are primarily found in the central nervous system (the brain and spinal cord.) CB2 receptors are primarily found in the peripheral nervous system like skin, muscles and other organs. These receptors respond to endocannabinoids and phytocannabinoids.

However, not all cannabinoids work the same way.

THC binds directly to these receptors, flooding the body with a large amount of a “bliss molecule” lookalike. This causes a high.

CBD does not bind directly to these receptors. Instead, CBD works indirectly by blocking enzymes that break down the body’s own anandamide. When there is more anandamide in the body, there is more CB1 activation and a more active and effective endocannabinoid system.

If THC grabs and hangs on to the receptors, think of CBD as a football lineman, blocking and tackling enzymes to make sure that anandamide (the guy with the ball), gets to the end zone.

Although CBD doesn’t bind directly to the CB1 or CB2 receptors, there are many, many other types of receptors in the brain. CBD does directly bond to some of these. Many of these receptors have anti-depressant, anti-psychoactive, anti-cancer and other functions.

You can see the CBD is immensely helpful in improving the overall function of the endocannabinoid system, which is to nudge the body back to balance when faced with illness or injury. CBD helps the body to heal itself.


  • Endocannabinoid System – A system that all mammals, birds, reptiles and fish have that works to keep the body in a state of equilibrium.
  • Neurotransmitter – A chemical compound that carries messages around the body to the various parts of the nervous system.
  • Endocannabinoid – Cannabinoid (chemical compound) that is produced in the animal body. A type of neurotransmitter.
  • Phytocannabinoid – Cannabinoid (chemical compound) that comes from the cannabis plant.
  • Anandamide – An endocannabinoid and neurotransmitter produced in the body that is a pleasure and reward regulator.
  • Cannabidiol (CBD) – A phytocannabinoid that works in the body to block enzymes that break down anandamide. In short, more anandamide in the body means a more active and effective endocannabinoid system.
  • Tetrahydrocannabinol (THC) – A phytocannabinoid that mimics anandamide. THC is what is responsible for the “high” people experience after the consumption of some cannabis products.

More Reading

For even more information on the endocannabinoid system, you may want to check out these articles and books!

How to Use CBD Oil for Migraines

Anyone that suffers from migraines can tell you they are far different than the every-once-in-a-while sporadic headache that many of us get from time to time.  Some studies suggest that up to 13% of adults in the United States suffer from migraines, and that migraines negatively impact the educational, professional or social activities of more than 90% of sufferers.

It’s no wonder that migraine suffers are so passionate (and relentless) about finding tools and treatments to treat their pain. One promising treatment is using CBD for migraine.

What is CBD Oil?

In case you aren’t already familiar with CBD oil, here is a quick primer.

CBD is short for cannabidiol, which is one of the many natural compounds known as phytocannabinoids found in the cannabis plant. You are probably most familiar with the most “famous” phytocannabinoid, which is THC (or tetrahydrocannabinol.) THC is responsible for the “high” when you ingest certain strains of cannabis.

These phytocannabinoids (like CBD and THC) work like little messengers that we already have in our bodies. The little messengers that already exist inside us are called endocannabinoids. Endocannabinoids work in our nervous system and are also important to our immune function.

One of the reasons for the growing popularity of CBD, is that it has so many benefits to the body, without the psychoactive effect of a “high.” CBD works to nourish the endocannabinoid system in the body.

Why Would CBD Help With Migraine?

Some studies have shown chemical reactions and changes in the brain of migraine sufferers, but we don’t know for sure exactly what causes migraines. The American Migraine Foundation classifies migraine as a “neurological disorder that is characterized by over excitability of specific areas of the brain.”

Even though we haven’t been able to explain exactly what causes migraine, we do know that many migraine sufferers often have personal triggers such as:

  • Stress
  • Fatigue
  • Foods and additives
  • Smells
  • Alcohol
  • Hormonal changes
  • Lights and sounds
  • Hunger or thirst

A few things that stand out on that list are stress, fatigue, and hormonal changes.

CBD is anti-inflammatory

We know that certain intolerance to food, additives, alcohol, and sugars can create inflammation in the body, creating disease. As an anti-inflammatory, CBD helps to reduce inflammation and swelling in the body, which can help minimize migraine triggers.

CBD is anti-anxiety

If stress and anxiety are a major trigger for your migraines, the calming and restoring effects of CBD may help.

CBD is an analgesic

While not a trigger, pain is a common symptom of migraine. CBD is a pain-reducer and can help to dull or eliminate the pain associated with migraine.

CBD Oil & Migraine Studies

There are several studies that explore the effectiveness of CBD on migraines, with more research on the horizon.

The first is a study by the European Academy of Neurology that explored the use of cannabinoids (CBD is one!) to treat migraine. In this study, cannabinoids reduced pain in 43.5% of patients. The cannabinoid combination also outperformed the pharmaceutical, amitriptyline, by 5%! You can read the study summary here.

Another study looked at the overall frequency of headaches in those that used CBD and other phytocannabinoids as a migraine therapy. In 121 adults, the frequency of headaches over a one month period went from 10.4 headaches, down to 4.6! You can read the complete study here.

While there may not be overwhelming evidence from scientific studies to prove the effectiveness of CBD to treat migraines, there is plenty of anecdotal evidence from personal experience and testimonials from those whose lives have been changed for the better! This particular study looks at a lot of this anecdotal evidence.

With the 2018 Farm Bill legalizing hemp products containing less than 0.3% THC, as well as a burgeoning public interest, we expect more (and better) research on the therapeutic benefits of CBD on migraines.

How to Use CBD for Migraines

CBD works better as a preventative measure for migraine than as an acute treatment after the onset of migraine. For this reason, the most effective CBD regimen against migraine is a daily one! CBD is a natural supplement that is non-habit forming and safe for daily use.

Several of the above-referenced studies pointed out the importance of finding an appropriate dose. We recommend keeping CBD in your system by taking it twice per day. You can start with a minimum dose of 25mg each morning and night, and adjust accordingly. Make it a part of your morning and nighttime routines!


We offer top-quality, pure tinctures in natural and peppermint flavors. The tincture is held under the tongue for 60 seconds, then swallowed. Holding the tincture under the tongue allows it to be absorbed quickly into the blood stream. The natural flavor is mild, but the peppermint is also tasty and lightly sweetened!

Gel Cap

We also have an easy to swallow gel cap that uses water soluble nanotechnology for maximum absorption. The effects of the CBD can be experienced quickly; within 15-20 minutes.

Please don’t hesitate to reach out to us with your migraine experiences, or questions about using CBD for migraine!

cannabis leaf on wooden plank with words how to use cbd oil for migraines

What is the difference between cbd oil and hemp oil, or hemp seed oil, or hemp extract?

What’s the Difference? CBD Oil vs Hemp Oil, Hemp Extract or Hemp Seed Oil

CBD Oil vs. Hemp Oil vs. Hemp Extract vs. Hemp Seed Oil

There is a lot of confusion about the differences between hemp oil vs. hemp seed oil, CBD oil, or hemp extract. Most of this confusion stems from the fact that hemp and marijuana plants are from the same Genus (or category) called Cannabis.

Within this Genus there are three species, but many subtypes, often called strains (but more properly called cultivars.)
People grow hemp for incorporation into other products. These products range from clothing to paper to makeup to cereal. Hemp is really a raw material. Think of it like other resources such as cotton and wood.

Using hemp as a raw material was common prior to early last century.  People used hemp for paper, for clothing, and for rope.

Hemp seed oil is most often sourced from the Cannabis Sativa plant seed, also known as Industrial Hemp. Hemp seed oil production is regulated, and is tested for THC and CBD levels. However, hemp seed oil contains neither of those cannabinoids. Tests have shown that there are no cannabinoids present in the seeds of the hemp plant.

Hemp Seed Oil Nutrition

So just some quick nutrition information! Hemp seed oil contains a fatty acid profile of 4:1. For most people, an omega-6 to omega-3 ratio of 4:1 is ideal–that’s 4 omega-6s for every 1 omega-3. Anti-aging experts suggest even smaller ratios, maintaining a 1:1 ratio or higher in favor of omega-3s. 4.

The average American eats a ratio of anywhere from 12:1 to 25:1 omega-6 to omega-3. Not good. So Hemp seed oil is a good option for an oil with a good fatty acid profile.

CBD Oil, Hemp Extract or Hemp Oil

CBD Oil, Hemp Extract or Hemp Oil (not hemp SEED oil) is an extract that contains naturally occurring terpenes, flavonoids, Cannabinoids, and other beneficial phytonutrients from the hemp plant. They often refer to CBD oil to as “Hemp Extract” or “Phytocannabinoid-Rich Hemp Oil.”

Cannabis Oil

Cannabis oil is commonly from the marijuana plant but can vary depending on the manufacturer as Cannabis is also the botanical name of the Industrial Hemp plant. Cannabis oil from the Marijuana strain is extracted from the Marijuana plant. It contains high levels of THC and lower levels of CBD Oil. Cannabis oil from the Marijuana plant is illegal in most states. People use it for medicinal purposes and as a recreational drug. Cannabis oil production is not regulated.

Hope Botanicals sells THC free products and well as one product that contains the federal allowable limit of THC at 0.3% or less.

FAQ: Questions and Answers

Q: Is Hemp seed oil the same as Hemp Extract/CBD Oil/Hemp Oil or medicinal cannabis oil?

A: No, Hemp seed oil and CBD oil both are made from the same plant though. Hemp seed oil is beneficial containing a lot of antioxidants and omega-3 and omega-6 fatty acids. Hemp seed oil is pressed from the seeds of the hemp plant. This means it contains little to no CBD or THC.  Hemp seed oil is often sold in 16oz bottles to 1 gallon jugs.

Q: Will CBD oil make me fail a drug test?

A: Depends. A lot of products contain a small amount of THC (usually the federal allowable amount of 0.3% or less) and if you use this, you will fail a drug test. If a drug test is a concern, you’ll want to find a product that contains 0 THC and says so on the label. If it doesn’t say “0 THC” on the label, it likely contains THC. Labs should be available on any product you purchase.

Another option is to purchase a CBD isolate which means all other cannabinoids and THC have been removed from the oil in a lab.

Hope Botanicals carries mostly 0 THC products, CBD isolate (called Hope Rx Clear) and one product, Super Full Spectrum Tincture, which contains 0.3% THC or less (0.3% is the federal allowable amount of THC). We use Hemp Seed Oil as the carrier oil for all our tinctures as we believe there is a natural occurring synergy between Hemp Seed Oil and CBD oil.

Q: How do I understand the label?

A. To delve further into the names for CBD oil, you will see labels that say “Full Spectrum” and “Broad Spectrum”. Full spectrum generally indicates the oil contains some THC, because full spectrum oil is mostly known as containing multiple cannabinoids, including THC. But with the advent of new extraction technology, labs can now extract the THC and leave behind multiple cannabinoids. So, to see a label that says “Full Spectrum with 0 THC” is not uncommon.

Broad Spectrum has generally been the term for oil that contains CBD with no THC, with slight amounts of other cannabinoids. Once again, new technology is enabling labs to extract the THC and leave behind other cannabinoids.

To emphasize the point, if you’re looking for a CBD product that contains 0 THC, look for “0 THC” on the label.

Hope Botanicals uses the terms CBD, Phytocannabinoid-rich Hemp Oil, Full Spectrum and Super Full Spectrum.

You can always contact us for more information on products. We know it can be confusing and we want to help you figure out which product is best for you, your horse and your pets.

CBD Oil vs. Hemp Oil. What is the difference? What is hemp extract and hemp seed oil?

The Top 8 Uses for CBD Oil

There is a lot of buzz circulating that celebrates the benefits of cannabidiol (CBD) for just about everyone suffering from any ailment. If you are just starting to research the benefits and uses of CBD, all of the wonderful success stories you hear might overwhelm you.

An infographic explaining the top uses for CBD oilUses for CBD Oil

Based on my research and the questions I frequently receive, here are the top 8 uses for CBD oil (in no particular order.)

Fibromyalgia Pain

Many women have asked me if CBD will help with Fibromyalgia. Doctors don’t know the cause of this painful issue, and Fibromyalgia sufferers are desperate for help. I took CBD for this condition and so I share my personal story. Within days of starting CBD, it helped to manage my pain and today I have little to no pain at all. I get a lot of feedback from women saying it helps control the pain, and that it works consistently.


The issue of our time. So many people are looking for relief from anxiety and are not willing to take, or are trying to get off of, traditional pharmaceutical options. The popular perception has been that you need THC for anxiety, but that is not true. In a clinical trial conducted at the South London and Maudsley NHS Foundation Trust in London, brain scans of participants given CBD revealed changes in blood flow to the regions of the brain linked to feelings of anxiety. You can read this research on CBD and anxiety here.


My first customer was a man with multiple myeloma blood cancer. He is in remission. There are many studies on CBD and cancer. NIH PubMed is a good resource for information. The side benefit that my customer didn’t know about is that CBD helped his kidney function. When opiates couldn’t control his pain, CBD did. You can read his story here.


Insomnia is a big issue that especially plagues women. CBD interacts with many receptors, proteins, and other chemicals in the brain. These interactions create changes in neurotransmitter activity, hormones, and other cells throughout the brain and body. Through these interactions, CBD appears to affect many of the body’s functions including sleep-wake cycles. For those with chronic insomnia, a slight amount of THC with CBD seems to be very beneficial. Using CBD within the federally allowable limit of THC (0.3%) would be a good option.


Many parents of children with ADHD are looking for other options to prescribed medications for their children. There are many forums for parents researching CBD for ADHD and other subtypes. There is limited research on CBD for ADHD, but observational studies show it helps reduce the anxiety and hyperactivity associated with ADHD.

An issue that should be addressed is that some research has included CBD with THC or even medical marijuana. Opponents of CBD for ADHD like to bring this to the forefront of their opposition to CBD for ADHD. There is a clear differentiation between CBD and CBD containing THC or medical marijuana. CBD products can be a fairly broad spectrum oil (containing other cannabinoids and terpenes) without THC. This distinction needs to be clear.


We have known for years how inflammation effects every part of our well-being. CBD has shown to radically reduce inflammation in the body. In 2018, WADA (World Organization for Doping in Athletes) took CBD off the prohibited substances list, as athletes have known for a long time how well CBD works for inflammation and pain. Unlike ibuprofen, it is therapeutic for your body and good for your liver.


I receive many inquiries about CBD for arthritis pain. I also get many testimonials from customers that CBD has given much pain relief. People feel better, begin walking, and the cycle of pain fades. The research on CBD for arthritis is extensive, including this one that used a topical application of CBD. The application showed significantly reduced joint swelling and thickening of the synovial membrane.

According to another study about the positive effects of cannabidiol on arthritis symptoms, CBD has also shown to actually reverse the effects of arthritis. Using CBD daily in the form of a tincture or gel cap, along with a topical salve is a great protocol for arthritis.


I have many people contact me to ask about CBD for seizures in people. There have been popular CBD brands that have proven to provide relief from seizures and have been used for a few years now. The FDA approved a by-product of CBD in June 2018 that had good results but horrible side effects. CBD with the legal limit (0.3%) of THC or less has been shown to control seizures with NO side effects. To be clear, never use CBD with THC for seizures in pets, as pets do not tolerate THC. CBD without THC has been shown to control seizures in pets. Please see my future blog post on how to use CBD for dogs.

There are many promising uses for CBD, with more on the horizon as research continues on this amazing compound.

The top 8 uses for CBD oil.

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