Peppermint Horse and People Tincture, 750mg, April 16, 2018
Hemp Pellets are pressed from Hemp Meal, which contains ZERO THC and a
guaranteed minimum cannabinoid content of 0.3% dry matter. They have been assayed to contain ≈ 20%
plant protein, 30% insoluble fiber and 50% complex carbohydrates. The Hemp Meal that these pellets are
pressed from have been sterilized and ground to a uniform mesh. A food-grade FDA-approved mold
inhibitor has been added to the pellets when pressed.
Dosage studies in the horse have found that horses are very sensitive to hemp oil, and generally need a
very low dosage relative to their weights. Dosage is dependent on severity of the horses condition, and
to some extent, its size.
These pellets can be easily administered to a variety of species, including horses, donkeys, mules, goats,
sheep, swine, poultry and pet caged birds, rabbits and pocket pets.
These pellets are guaranteed to contain a minimum of 0.3% phytocanabinoids, or 3 mg for each gram of
pellets. Volume measurement approximates the concentration to be 3 mg for each level teaspoon which
would be no less than 9-10 mg per teaspoon. This makes each level Tablespoon to contain 25-30 mg of
PCR, which would be a single dose for a horse.
This is Boogie. He’s about 15 years old and developed pockets of inflammation on his knees due to arthritis. His owner thought he was done competing but then she tried the CBD pellets by Hope Botanicals. After a week and a half on the pellets, a week which included a three day trailer ride, the inflammation on his knees is down to almost nothing. We know CBD is very anti-inflammatory and can help with lots of issues, but this is amazing!
This is Whiskey. His owner started giving him the Full Spectrum Oil, Natural Flavor, for his fatty tumors. Six days later they were reduced by half. One has gone from golf ball size to lima bean size in two weeks. Not only are his tumors smaller, he’s playing like a young dog. Makes us all smile:)
CBD helps with sleep. We know this from using it ourselves but have heard from numerous customers that, yes, our CBD does work. Research studies have validated the use of CBD for sleep.
Full Spectrum and Isolate
I see lots of people complaining that CBD doesn’t work. You’ve got to get the right amount from the right product. Although some people believe in the effectiveness of isolate, which is pure CBD, we’re starting to understand the great benefits of full spectrum CBD.
Get Full Spectrum
Watch for Full Spectrum CBD that is grown and processed in the USA using C02 extraction and organic practices. Be wary of products from China or other countries. Labs may buy product from other countries and bottle it here and not label the country of origin for the CBD.
Our Full Spectrum CBD has all the goodies of a marijuana plant including CBD, CBN, CBG plus terpenes and plant lipids, without THC. All these together form the entourage effect. These compounds hit the cannabinoid receptors in your body to heal and nourish.
Understand the dosing
If you buy a 250mg bottle of CBD because it’s inexpensive, that’s great. Just understand that 1/2 a dropper of 250mg tincture gives you maybe 8.3 mg in a half a dropper full. Not enough for even a small dog. (yes, dogs can have CBD!) Most people require a minimum dose of 25mg. Consequently, this may be why some people are saying CBD isn’t working for them.
We’ve made the dosing simple. One drop equals one mg of CBD. It’s that easy. So when you’re looking for CBD, rest assured that ours is Full Spectrum, made and grown in the USA with organic practices and no THC.
Review: Cannabinoid Use in the Management of Gastrointestinal Symptoms
A review published in Current Gastroenterology Reports in February 2015 examined the role of cannabinoids in the treatment of gastrointestinal (GI; the system involved in ingestion and digestion of food, and excretion of waste) symptoms like nausea, vomiting, and visceral pain (pain that originates from in/around organs) and found that certain targeted cannabinoid therapies may be useful in GI disease/disorder management.
Background: Cannabinoid Effects on the GI System
The researchers note that modulation of the endocannabinoid system (especially the type of cannabinoid receptor found most frequently in the gastrointestinal system, known as CB1 receptors) may regulate:
- food intake
- nausea and vomiting
- stomach secretion (the cells of the stomach release acid to digest food)
- stomach protection (if the stomach isn’t protected, it can get damaged by the acidic secretions)
- GI motility/movement (too much movement –> diarrhea, too little movement –> constipation)
- ion transport (absorption and secretion –> e.g. maintaining proper fluid/electrolyte [e.g. salt] balance)
- internal organ sensation
- the inflammation process that results from certain GI illnesses
- the number of cells of the GI tract (too many cells may indicate cancer or a disease process, too few may lead to tissue injury)
They also note that modulation of another type of cannabinoid receptor (CB2) which are found most commonly in cells of the immune system (which helps the body recover from, or prevent, sickness/injury) can help:
- regulate motility/movement
- control the inflammation process that results from certain GI illnesses
- in reducing internal pain and sensation
Findings of the Review
Visceral pain (pain in/around the organs) is caused by over-stretching, lack of blood flow, or a destructive inflammatory process. Individuals often feel the pain in multiple areas and have trouble figuring out exactly where the pain is coming from.
Patients with the GI symptom of visceral pain most commonly have either (1) non-ulcerating stomach pain or (2) irritable bowel syndrome (IBS). Irritable bowel syndrome can cause diarrhea, constipation, gas, and pain, causing a severe decrease in patients’ quality of life, and results in millions of health visits and a cost of billions of dollars every year, so finding safe, effective treatments would provide a wide range of benefits.
Overall, researchers found that in animal studies, cannabinoids stimulated CB1 and CB2 receptors, as well as another receptor known as TRPV1, resulting in:
- pain relief and decreased sensation in the abdomen
- decreased motility (i.e. less movement of the bowel walls –> less diarrhea)
- decreased sensitivity to stretching (wave-like tightening and relaxation of the gut causes digested food to move towards the rectum to be expelled as waste- it can be triggered by stretching of the bowel walls, which happens when the bowels become full- excessive stimulation of this process can result in diarrhea)
Another study, using mice acting as models for humans with GI disorders, found that an agent that stops the action of an enzyme that breaks down the endocannabinoid anandamide (and therefore increases levels of anandamide in the body) was able to prevent excessive movement of the gut wall and reduced pain.
However, in the human studies assessed, two studies found that administration of synthetic, isolated THC either (1) decreased sensitivity to stretching, but did not affect pain sensation or (2) had no effect on sensitivity. However, in a test of function of the esophagus (food travels from the mouth, through the esophagus, and into the stomach), another study found that treatment with THC after the test (but not before) decreased sensitivity to stretching and relieved pain. Also, given the results of the animal studies, it’s possible that other cannabinoids besides THC, or a combination of THC plus other cannabinoids, may be effective in controlling gut wall movement and pain.
Of the pain studies reviewed, side effects were mild and included sleepiness, an increase in awareness of one’s surroundings, light-headedness, and an increase in heart rate.
Nausea and Vomiting
Nausea and vomiting can be caused by diseases/disorders, pregnancy, and motion sickness, or as a side effect of commonly used medications or treatments, such as chemotherapy. It is caused by stimulation of certain areas of the brain that have receptors for the signaling molecules dopamine and serotonin, and cannabinoids (CB1 receptors). Nausea and vomiting can have a severely negative impact on quality of life, especially for people who experience them frequently.
In one study analyzed by the authors, they found that in a test of motion sickness, those individuals who experienced nausea with movement had (1) lower levels of the endocannabinoids 2-AG and anandamide, (2) fewer active CB1 receptors, and (3) increased levels of an endocannabinoid breakdown product, than those who did not experience nausea. This means that an increase in endocannabinoids or cannabinoid receptor stimulation may have been protective against nausea.
Isolated, synthetic THC has been used for cancer patients with chemotherapy-induced nausea and vomiting. In one study, it was found to be more useful than dopamine receptor blockers, and in another it was comparably effective to dopamine receptor blockers when used with another chemotherapy drug that causes vomiting, called cisplatin. Even though the synthetic THC was not more effective, these results are still important given that dopamine antagonists may have serious side effects.
In another study, synthetic THC was similarly effective as serotonin receptor blockers, and even more so when it came to “mild-moderately severe” nausea. Another study of Sativex (a compound with equal parts THC and CBD), demonstrated that the addition of Sativex to an anti-nausea/vomiting treatment helped to prevent nausea and vomiting even more, with few and mild symptoms.
The researchers also recommend further research into agents that activate only CB2 receptors, or CB1/CB2 receptors in areas of the body other than the nervous system, in order to prevent the psychoactive effects of cannabis (those that occur when someone is intoxicated by cannabis, or “high”). However, in some cases, stimulation of receptors that lead to intoxication (or the “high” produced by cannabis with higher concentrations of THC) may be necessary for optimal management.
Given the safety profile of endocannabinoid modulation and phytocannabinoids (i.e. cannabinoids found in cannabis) and the debilitating nature of many GI disorders/diseases, increased research into their management with the use of various cannabinoids is warranted. Increased research will help to determine (1) which GI disorders, diseases, and symptoms cannabinoid therapies may be useful for and (2) what type of cannabinoid therapy is best in each situation.
According to the researchers, “In conclusion, our review suggests that cannabinoids have the potential to play a vital role in the modulation of nausea, vomiting, and possibly visceral pain. Although the jury is still out on determining the “magic drug,” it seems that with the development of newer ligands [agents that bind to receptors, e.g. cannabinoids], the future appears promising.”
For information on reasonable expectations and safety in considering whole-plant medical cannabis use, as well as how you can advocate to move cannabis out of the Schedule I controlled substance classification in order to increase research on phytocannabinoids in the United States, click here.
The following is a testimonial we received.
My husband was diagnosed with Multiple Myeloma July 7, 2017. Multiple Myeloma is a cancer formed by malignant plasma cells. This particular type of cancer affects many things, low blood counts, difficulty fighting infections, bone and calcium issues and kidney problems to name a few. When diagnosed, my husband had a creatinine level of 3.88 mg/dl. His numbers continued to climb to 4.37 by mid-July. Normal range is 0.60-1.30 mg/dl. Creatinine levels are a direct correlation of kidneys function and my husband was considered in kidney failure and dangerously close to having start dialysis.
He started taking Hope Botanicals Softgels 25 Mg. twice daily, mostly to see if it would help with fatigue, mood and sleep. The surprising thing was that his creatinine levels started going down. Being an average male, he didn’t like taking so many medications and cut the non-prescribed CBD from his regime after a few weeks. Once again, his creatinine levels started climbing and he was back to being tired and sluggish. He resumed taking the capsules and his levels started going down again and are presently 2.1 mg/dl.
His mood is better, he feels better, in fact so much so that he cut 6 cords of wood this past week.
I have had a 10 year odyssey of feeling like crap. Hormones and stress were the major culprits, and of course stress can do things to our body that we don’t even know.
I have been seeing a naturopath for 2 years and we seemed to be getting closer to finding out some of my issues, but in the meantime she recommended I take CBD that she sold in her office. I was wary as I had tried marijuana (legal in my state) and I had no idea that a little THC could make me totally nuts. I was very skeptical and super nervous but assured me it contained no THC so I tried it and it really helped. Each pump was only 3 mg (there’s that dosing issue again! Primates can start with 25 mg) so I was squirting that stuff in my mouth like crazy trying to sleep. The only problem was that it contained monk fruit and some other stuff. After 10 squirts two times a day for a few days my stomach was not happy!
I started researching CBD that I could take that didn’t contain anything else like herbs or monk fruit. This was harder than I thought and proved almost impossible to find. In stores and online want to sell you a bottle with 325mg of CBD, which is 6.5 doses! We traveled to another state and I ran out. I am always desperate to sleep so we went in a shop that sold CBD. I had to pay $100 for 325 mg of CBD in glycerin and some kind of nasty sweetener that wouldn’t even come out of the dropper. I was getting desperate to find some resource for CBD.
In the meantime, I decided if it was good for me it was good for my horse! So I found a dog version of CBD, and of course they wouldn’t tell me how much CBD was in the bottle I was buying, only how many drops to give the horse. Frustrating again! But it worked on the horse (for stall rest) like nothing else (ace, sedavet, etc) so I started taking the dog CBD!
I read about a vet in Colorado that works with a company that makes CBD for animals and humans. (PS: It’s all the same thing, just different dosing and dogs can’t have flavoring that’s in the people CBD). So I called and talked to him and decided to start my own CBD company so that me, my family, friends and horse would have a consistent, pure supply of CBD.
I’ve now been using their product for 8 months on myself and the horse. The consistency is great. The horse stays the same on 50 mg per day. He’s not needing more and more to get the same affect. This is really encouraging!
So anyway, that’s most of my CBD story. I have more incidents to tell about other folks and other horses. More to come …..